Original algorithm from B1851202 SAP defines a 3 class risk group:
Details
High-risk (immunocompromised)
Asplenia - not supported
Cancer/Malignancy, Hematologic - OK
Cancer/Malignancy, Solid Tumor - OK
Chronic Kidney Disease - OK
Human Immunodeficiency Virus (HIV) – AIDS - OK
Human Immunodeficiency Virus (HIV) – No AIDS - OK
Immunodeficiency - OK
Immunosuppressant Drug Therapy - OK
Organ Transplantation - OK
Multiple Myeloma - not supported
At Risk (immunocompetent)
Asthma - OK
Alcoholism - OK
Celiac Disease - not supported
Chronic Liver Disease without Hepatic Failure - OK
Chronic Liver Disease with Hepatic Failure - OK
Chronic Obstructive Pulmonary Disease - OK
Cochlear Implant - not supported
Congestive Heart Failure - OK
Coronary Artery Disease (CAD) - OK
Chronic Neurologic Diseases - OK
Coagulation factor replacement therapy - not supported
CSF Leak - not supported
Diabetes Treated with Medication - OK
Down syndrome - OK
Institutionalized in nursing home or LTC facility (Nursing home or long-term care facility for those with disability or dependency on subject characteristics/risk determinants eCRF page) - OK
Occupational risk with exposure to metal fumes - OK
Other Chronic Heart Disease - OK
Other Chronic Lung Disease - OK
Other pneumococcal disease risk factors - OK
Previous Invasive Pneumococcal Disease - not supported
Tobacco smoking (Tobacco/E-Cigarettes) - OK
Anything else is low risk